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儿童复发性葡萄球菌烫伤样皮肤综合征:两例报告

Recurrent staphylococcal scalded skin syndrome in children: report of two cases.

作者信息

Machang'u R S, Mgode G, Gisakanyi N

机构信息

Faculty of Veterinary Medicine, Department of Veterinary Microbiology, Sokoine University of Agriculture, Morogoro, Tanzania.

出版信息

East Afr Med J. 1997 Sep;74(9):603-4.

PMID:9487441
Abstract

A localised "scalded skin syndrome" occurred in two male siblings aged five and ten years old, in Morogoro, Tanzania. This condition recurred in the same children within a period of about 12 months. A haemolytic ampicillin resistant Staphylococcus aureus was isolated from the bullous material, suggesting that the condition was staphylococcal scalded skin syndrome (SSSS). This implies that the bacterial isolate was an exfoliative toxin (ET) producing S. aureus. This infection was, however, striking because SSSS occurs mostly in newborns, and it is rarely recurrent. It is possible that a new strain with particular adaptability, or an inherent susceptibility to the S. aureus of the affected children was the cause of this recurrency.

摘要

在坦桑尼亚的莫罗戈罗,两名分别为5岁和10岁的男性同胞出现了局限性“烫伤样皮肤综合征”。这种情况在大约12个月内于同一儿童身上复发。从水疱性物质中分离出一株对氨苄西林耐药的溶血性金黄色葡萄球菌,提示该病症为葡萄球菌烫伤样皮肤综合征(SSSS)。这意味着分离出的细菌是一株产剥脱毒素(ET)的金黄色葡萄球菌。然而,这种感染很引人注目,因为SSSS大多发生在新生儿中,且很少复发。有可能是一种具有特殊适应性的新菌株,或者是患病儿童对金黄色葡萄球菌存在内在易感性导致了这种复发。

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