Mangura B T, Passannante M R, Reichman L B
University of Medicine and Dentistry of New Jersey, Department of Medicine, Newark, USA.
Int J Tuberc Lung Dis. 1997 Dec;1(6):576-8.
Measures known to improve adherence such as short course chemoprophylaxis and directly observed therapy can be enhanced to a significant extent/by the use of incentives. Adherence to tuberculosis therapy is influenced by several factors, including the health care system, complexity of therapeutic regimens and patient's characteristics. Individual factors that negatively influence patient's adherence are the most difficult to counter. Preventive tuberculosis therapy is doubly challenging because the benefit of treatment is not felt, while toxicity from the medication, when it occurs, is experienced immediately. Ingenious incentives therefore have to make it worth the patient's while. During a study on preventive regimens, a request for an incentive, Sustacal, was observed to help completion of preventive regimens. Components of individual TB programs may help in patient adherence; it is important for health care staff to identify these aspects and, if they are successful, utilize these as an incentive to complete treatment.
已知的提高依从性的措施,如短程化学预防和直接观察治疗,通过使用激励措施可在很大程度上得到加强。对结核病治疗的依从性受多种因素影响,包括医疗保健系统、治疗方案的复杂性和患者特征。对患者依从性产生负面影响的个体因素最难应对。预防性结核病治疗面临双重挑战,因为治疗的益处无法感受到,而药物毒性一旦出现则会立即被体验到。因此,巧妙的激励措施必须让患者觉得值得。在一项关于预防方案的研究中,观察到对一种名为苏太卡(Sustacal)的营养补充剂的需求有助于完成预防方案。个别结核病项目的组成部分可能有助于患者的依从性;医护人员识别这些方面很重要,如果这些方面取得成功,可将其用作完成治疗的激励措施。