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卡氏肺孢子虫中耳炎

[Pneumocystis carinii otitis].

作者信息

Biermann E

机构信息

HNO-Abteilung des Allgemeinen Krankenhauses St. Georg, Hamburg.

出版信息

Laryngorhinootologie. 1997 Dec;76(12):745-8. doi: 10.1055/s-2007-997518.

Abstract

Pneumocystis carinii (PC) otitis is a rare opportunistic infection of the acquired immunodeficiency syndrome (AIDS). Initially hearing loss and otalgia occur with thickening of the tympanic membrane and the bordering skin of the ear canal. Otorrhea, ear polyps, perforation of tympanic membrane, destruction of mastoidal bone, and participation of cranial nerves are observed. Diagnosis is established histologically. The treatment of the parasite is by trimethoprim-sulfamethoxazole combinations. The immunological situation seems to be better than in PC pneumonia. Due to the underlying immunological incompetence the infection can not be expected to limit itself. To prevent severe complications as sequestrating mastoiditis, early diagnosis and specific surgical and medical treatment are necessary.

摘要

卡氏肺孢子虫中耳炎是获得性免疫缺陷综合征(艾滋病)一种罕见的机会性感染。最初出现听力丧失和耳痛,同时鼓膜及耳道毗邻皮肤增厚。可见耳漏、耳息肉、鼓膜穿孔、乳突骨破坏及脑神经受累。通过组织学检查确诊。寄生虫的治疗采用甲氧苄啶 - 磺胺甲恶唑联合用药。免疫状况似乎比卡氏肺孢子虫肺炎时要好。由于潜在的免疫功能不全,预计感染不会自行局限。为预防严重并发症如乳突炎,早期诊断以及特定的手术和药物治疗是必要的。

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