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卡氏肺孢子虫中耳炎

[Pneumocystis carinii otitis].

作者信息

Biermann E

机构信息

HNO-Abteilung des Allgemeinen Krankenhauses St. Georg, Hamburg.

出版信息

Laryngorhinootologie. 1997 Dec;76(12):745-8. doi: 10.1055/s-2007-997518.

DOI:10.1055/s-2007-997518
PMID:9487488
Abstract

Pneumocystis carinii (PC) otitis is a rare opportunistic infection of the acquired immunodeficiency syndrome (AIDS). Initially hearing loss and otalgia occur with thickening of the tympanic membrane and the bordering skin of the ear canal. Otorrhea, ear polyps, perforation of tympanic membrane, destruction of mastoidal bone, and participation of cranial nerves are observed. Diagnosis is established histologically. The treatment of the parasite is by trimethoprim-sulfamethoxazole combinations. The immunological situation seems to be better than in PC pneumonia. Due to the underlying immunological incompetence the infection can not be expected to limit itself. To prevent severe complications as sequestrating mastoiditis, early diagnosis and specific surgical and medical treatment are necessary.

摘要

卡氏肺孢子虫中耳炎是获得性免疫缺陷综合征(艾滋病)一种罕见的机会性感染。最初出现听力丧失和耳痛,同时鼓膜及耳道毗邻皮肤增厚。可见耳漏、耳息肉、鼓膜穿孔、乳突骨破坏及脑神经受累。通过组织学检查确诊。寄生虫的治疗采用甲氧苄啶 - 磺胺甲恶唑联合用药。免疫状况似乎比卡氏肺孢子虫肺炎时要好。由于潜在的免疫功能不全,预计感染不会自行局限。为预防严重并发症如乳突炎,早期诊断以及特定的手术和药物治疗是必要的。

相似文献

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[Pneumocystis carinii otitis].卡氏肺孢子虫中耳炎
Laryngorhinootologie. 1997 Dec;76(12):745-8. doi: 10.1055/s-2007-997518.
2
Pathologic quiz case 2. Pneumocystis carinii infection of the external auditory canal.病理病例测验 2. 外耳道卡氏肺孢子菌感染。
Arch Otolaryngol Head Neck Surg. 1993 Apr;119(4):466-7, 469.
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Otic pneumocystosis in acquired immune deficiency syndrome.
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Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient.一名人类免疫缺陷病毒阳性患者双侧耳息肉中的卡氏肺孢子虫感染。
J Laryngol Otol. 2002 Apr;116(4):288-90. doi: 10.1258/0022215021910555.
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Pneumocystis carinii infection in the middle ear.中耳卡氏肺孢子虫感染
Arch Otolaryngol Head Neck Surg. 1992 Mar;118(3):269-70. doi: 10.1001/archotol.1992.01880030051012.
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Pneumocystis carinii in AIDS patients.艾滋病患者中的卡氏肺孢子虫。
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Comparison of atovaquone (566C80) with trimethoprim-sulfamethoxazole to treat Pneumocystis carinii pneumonia in patients with AIDS.阿托伐醌(566C80)与甲氧苄啶-磺胺甲恶唑治疗艾滋病患者卡氏肺孢子虫肺炎的比较。
N Engl J Med. 1993 May 27;328(21):1521-7. doi: 10.1056/NEJM199305273282103.
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An unusual case of Pneumocystis carinii presenting as an aural mass.一例罕见的卡氏肺孢子虫病表现为耳部肿物。
J Laryngol Otol. 1999 Jun;113(6):555-7. doi: 10.1017/s0022215100144469.
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Otic and ophthalmic pneumocystosis in acquired immunodeficiency syndrome. Report of a case and review of the literature.获得性免疫缺陷综合征中的耳部和眼部肺孢子菌病。1例报告及文献复习。
Arch Pathol Lab Med. 1992 May;116(5):500-3.
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Pneumocystis prophylaxis and survival in patients with advanced human immunodeficiency virus infection treated with zidovudine. The Zidovudine Epidemiology Group.接受齐多夫定治疗的晚期人类免疫缺陷病毒感染患者的肺孢子菌预防与生存情况。齐多夫定流行病学研究组。
Arch Intern Med. 1992 Oct;152(10):2009-13.

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