Salvatore S, Khullar V, Anders K, Cardozo L D
Department of Obstetrics and Gynaecology, King's College Hospital, London, UK.
Br J Urol. 1998 Feb;81(2):211-4. doi: 10.1046/j.1464-410x.1998.00537.x.
To compare the diagnoses derived from a retrospective analysis of 50 ambulatory urodynamic recordings, unaware of the final diagnosis, and to evaluate the importance of the symptom diary and the presence of two transducers in the bladder rather than one.
Fifty women underwent ambulatory urodynamics (duration 4 h) after video cysto-urethrography. A single solid-state microtip pressure catheter was inserted with both transducers inside the bladder, and another was inserted in the rectum. The women were asked to complete a symptom diary and the results were analysed with the active participation of the patient. Detrusor 'instability' was diagnosed on ambulatory urodynamics if there was a simultaneous increase in detrusor pressure and in the 'urethral' line in the presence of symptoms (urgency or leakage). All 50 recordings were analysed retrospectively in four combinations, i.e. with and without the additional 'urethral' line displayed on the screen and with and without the diary information. The total number of detrusor contractions was then calculated for each reading and 'abnormal detrusor activity' diagnosed when a contraction occurred with or without symptoms as recorded in the diary. The final diagnosis for each reading was then compared with that made at the time of the test with the patient present.
Using the information from the diary reduced the number of pressure rises classified as 'abnormal detrusor activity' by 58%; using a second bladder pressure transducer further reduced the number of pressure rises classified as 'abnormal' by 19%. Overall, using both techniques together reduced the number of spurious pressure rises misclassified as 'abnormal detrusor activity' by 64%.
Both the symptom diary and the placement of two transducers in the bladder can decrease, by almost two-thirds, the diagnosis of pathological detrusor activity on ambulatory urodynamics.
对50份动态尿动力学记录进行回顾性分析,在不知最终诊断结果的情况下比较诊断情况,并评估症状日记以及膀胱中使用两个而非一个传感器的重要性。
50名女性在进行膀胱尿道造影后接受了动态尿动力学检查(持续4小时)。将一根带有两个传感器的固态微尖端压力导管插入膀胱内,另一根插入直肠。要求这些女性填写症状日记,并在患者积极参与的情况下对结果进行分析。如果在出现症状(尿急或漏尿)时逼尿肌压力和“尿道”通道同时升高,则在动态尿动力学检查中诊断为逼尿肌“不稳定”。对所有50份记录进行回顾性分析,分为四种组合,即屏幕上显示或不显示额外的“尿道”通道,以及有或没有日记信息。然后计算每次读数时逼尿肌收缩的总数,并根据日记中记录的有无症状来诊断“异常逼尿肌活动”。然后将每次读数的最终诊断结果与患者在场时测试时做出的诊断结果进行比较。
使用日记中的信息可使被归类为“异常逼尿肌活动”的压力升高次数减少58%;使用第二个膀胱压力传感器可使被归类为“异常”的压力升高次数进一步减少19%。总体而言,同时使用这两种技术可使被误分类为“异常逼尿肌活动”的假性压力升高次数减少64%。
症状日记和在膀胱中放置两个传感器均可使动态尿动力学检查中病理性逼尿肌活动的诊断减少近三分之二。