纵隔霍奇金淋巴瘤化疗后的放疗：针对巨大肿瘤不同剂量放疗的结果
Radiation following chemotherapy for mediastinal Hodgkin's disease: the outcome of various doses for bulky tumors.
作者信息
Eisbruch A, Kazerooni E A, Sahijdak W M, Francis I R, Lichter A S
机构信息
Department of Radiation Oncology, University of Michigan, Ann Arbor 48109, USA.
出版信息
Radiother Oncol. 1998 Jan;46(1):47-9. doi: 10.1016/s0167-8140(97)00161-8.
Twenty-one patients with bulky mediastinal disease responding to chemotherapy received consolidation with low-dose mediastinal radiation (19.8-25.2 Gy). Their 5-year mediastinal failure rate (10%) was equivalent to that of 10 similar patients who received higher doses of 30-44 Gy (20%). Low-dose radiation may be appropriate for these patients. Prospective studies are required to verify these findings.
21例对化疗有反应的纵隔肿物患者接受了低剂量纵隔放疗（19.8 - 25.2 Gy）巩固治疗。他们的5年纵隔失败率（10%）与10例接受30 - 44 Gy更高剂量放疗的类似患者（20%）相当。低剂量放疗可能适用于这些患者。需要进行前瞻性研究来验证这些发现。
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