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[链激酶的异质性]

[The heterogeneity of streptokinases].

作者信息

Gerlach D, Köhler W

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1979;106(5-6):908-14.

PMID:94885
Abstract

Purified streptokinases of some strains of different types of Strep. pyrogenes (group A) as well as streptokinases of a strain of group C or group G streptococci, resp., were studied in regard of their heterogeneity. Differences of the streptokinases were found in their amino acid compositions and in isoelectric points. Serological differences were detected by a quantitative precipitation reaction with fluorescein-coupled antistreptokinase antisera from the goat as well as by neutralization reactions of the activator activities of the streptokinases by antistreptokinase antisera obtained from guinea pigs.

摘要

对不同类型的化脓性链球菌(A组)某些菌株的纯化链激酶以及C组或G组链球菌菌株的链激酶的异质性进行了研究。发现链激酶在氨基酸组成和等电点方面存在差异。通过与山羊来源的荧光素偶联抗链激酶抗血清的定量沉淀反应以及通过豚鼠来源的抗链激酶抗血清对链激酶激活剂活性的中和反应检测到血清学差异。

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