Strathdee S A, Patrick D M, Archibald C P, Ofner M, Cornelisse P G, Rekart M, Schechter M T, O'Shaughnessy M V
BC Centre for Excellence in HIV/AIDS, St Paul's Hospital, Vancouver, BC, Canada.
Addiction. 1997 Oct;92(10):1339-47.
Despite the fact that needle exchange was introduced in Vancouver as early as 1988, needle sharing remains common. An analysis was conducted to identify determinants of borrowing used needles among subjects participating in a case-control study. IDUs had a documented HIV seroconversion after 1 January, 1994 (n = 89), or repeatedly tested HIV-seronegative after this date (n = 192). Interviewer-administered questionnaires focused on drug use, sexual behaviours, source of needles and depression. Subjects were asked if they had "ever been forced to have sex" as a child, youth or adult. Logistic regression identified determinants of borrowing needles. After controlling for HIV serostatus, factors independently associated with borrowing were injecting > 4 times/day, polydrug use, and ever experiencing non-consensual sex (AOR = 3.4, 95% CI: 1.8, 6.5). Depression was associated with borrowing, although not independently so. Homosexual activity was independently associated with borrowing among males, whereas living with a sexual partner was an independent predictor for females. Access or barriers to clean needle use were not associated with borrowing. Social determinants, particularly a history of sexual abuse, are among the most significant predictors of needle borrowing among Vancouver's IDUs. Early identification of these factors should be a component of HIV prevention programmes.
尽管早在1988年温哥华就引入了针头交换项目,但共用针头的现象仍然很普遍。对参与一项病例对照研究的受试者中借用用过的针头的决定因素进行了分析。注射吸毒者在1994年1月1日之后有记录的HIV血清转化(n = 89),或在此日期之后多次检测HIV血清阴性(n = 192)。由访谈员管理的问卷集中在药物使用、性行为、针头来源和抑郁方面。受试者被问及他们在儿童、青少年或成年时期是否“曾被迫发生性行为”。逻辑回归确定了借用针头的决定因素。在控制了HIV血清状态后,与借用独立相关的因素包括每天注射超过4次、使用多种药物以及曾经历过非自愿性行为(比值比 = 3.4,95%置信区间:1.8,6.5)。抑郁与借用有关,尽管不是独立相关。同性恋活动在男性中与借用独立相关,而与性伴侣同居是女性借用的独立预测因素。获得清洁针头的途径或障碍与借用无关。社会决定因素,特别是性虐待史,是温哥华注射吸毒者中借用针头的最重要预测因素之一。尽早识别这些因素应成为HIV预防项目的一部分。