一种高效的脂质体介导的基因转移至鸡胚鳃弓、神经管和心脏的方法；一种阐明器官发生的策略。
An efficient liposome-mediated gene transfer into the branchial arch, neural tube and the heart of chick embryos; a strategy to elucidate the organogenesis.
作者信息
Yamada G, Nakamura S, Haraguchi R, Sakai M, Terashi T, Sakisaka S, Toyoda T, Ogino Y, Hatanaka H, Kaneda Y
出版信息
Cell Mol Biol (Noisy-le-grand). 1997 Dec;43(8):1165-9.
PMID:9489941
Abstract
Hemagglutinating virus of Japan (HVJ)-liposome mediated gene-transfer permitted to clarify the mechanisms of embryonic organogenesis of the branchial arches, neural tubes and heart by micro-injecting reporter-plasmid DNA, containing the Escherichia coli LacZ gene, in embryos at several stages.
摘要
日本血凝病毒（HVJ）脂质体介导的基因转移，通过在几个阶段的胚胎中显微注射含有大肠杆菌LacZ基因的报告质粒DNA，得以阐明鳃弓、神经管和心脏的胚胎器官发生机制。
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