Perepech N B, Nedoshivin A O
NII of Cardiology, Saint Petersburg.
Klin Med (Mosk). 1997;75(10):52-4.
Echocardiography and integral body rheography were made in 174 patients with macrofocal myocardial infarction (MI) to study hemodynamics at six stages of hospital rehabilitation (MI day 1-28). 97 patients received neoton (4 different scheme) in the acute period of MI. Neoton administration was found to prevent progressive left ventricular dilation and emergence of cardiac insufficiency in subacute period of MI, to reduce the risk of cardiac aneurism, recurrence and postinfarction angina. The response to neoton rises with an increase of its dose on the first day of the disease and lessening of the time span from first symptoms of MI and first neoton injection. An optimal scheme of neoton use is proposed.
对174例大面积心肌梗死(MI)患者进行了超声心动图和全身血流图检查,以研究住院康复六个阶段(MI第1 - 28天)的血流动力学。97例患者在MI急性期接受了新托宁(4种不同方案)。发现新托宁给药可预防MI亚急性期左心室渐进性扩张和心脏功能不全的出现,降低心脏动脉瘤、复发和梗死后心绞痛的风险。在疾病第一天新托宁剂量增加以及从MI首发症状到首次注射新托宁的时间间隔缩短时,对新托宁的反应增强。提出了新托宁使用的最佳方案。