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Rapid simultaneous screening of factor V Leiden and G20210A prothrombin variant by multiplex polymerase chain reaction on whole blood.

作者信息

Gomez E, van der Poel S C, Jansen J H, van der Reijden B A, Lowenberg B

出版信息

Blood. 1998 Mar 15;91(6):2208-9.

PMID:9490710
Abstract
摘要

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Rapid simultaneous screening of factor V Leiden and G20210A prothrombin variant by multiplex polymerase chain reaction on whole blood.
Blood. 1998 Mar 15;91(6):2208-9.
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Simultaneous allele-specific amplification: a strategy using modified primer-template mismatches for SNP detection--application to prothrombin 20210A (factor II) and factor V Leiden (1691A) gene mutations.同时等位基因特异性扩增:一种利用修饰的引物-模板错配进行单核苷酸多态性检测的策略——应用于凝血酶原20210A(因子II)和因子V莱顿(1691A)基因突变检测
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Analytical evaluation of primer engineered multiplex polymerase chain reaction-restriction fragment length polymorphism for detection of factor V Leiden and prothrombin G20210A.用于检测凝血因子V莱顿突变和凝血酶原G20210A的引物工程化多重聚合酶链反应-限制性片段长度多态性分析评估
J Mol Diagn. 2000 Aug;2(3):153-7. doi: 10.1016/S1525-1578(10)60631-9.