Graeff-Teixeira C, Agostini A A, Camillo-Coura L, Ferreira-da-Cruz M F
Department of Immunology, WHO Collaborating Center for Research and Training in the Immunology of Parasitic Diseases, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil.
Trop Med Int Health. 1997 Mar;2(3):254-60. doi: 10.1046/j.1365-3156.1997.d01-266.x.
Abdominal angiostrongyliasis is a nematode disease produced by Angiostrongylus costaricensis, a metastrongylid parasite of wild rodents. Accidental human infection occurs through ingestion of food or water contaminated with third-stage larvae present in the mucous secretion of terrestrial molluscs. An ELISA test was standardized for detection of IgG antibodies recognizing a surface antigen prepared from female worms. Competitive absorption of sera with Ascaris suum crude antigen resulted in a test with 86% sensitivity and 83% specificity. The disease is endemic in Southern Brazil and a number of cases are diagnosed every year through anatomo-pathological examination of biopsies or surgical specimens, since no other diagnostic method is available. According to seroepidemiological studies, prevalences in two transmission foci are 29.8 and 66%, attesting to the widespread occurrence of the infection in those endemic areas.
腹部管圆线虫病是由哥斯达黎加管圆线虫引起的一种线虫病，哥斯达黎加管圆线虫是野生啮齿动物的后圆线虫寄生虫。人类因误食被陆生软体动物黏液分泌物中第三期幼虫污染的食物或水而意外感染。一种酶联免疫吸附测定（ELISA）试验已标准化，用于检测识别从雌虫制备的表面抗原的IgG抗体。用猪蛔虫粗抗原对血清进行竞争性吸收后，该试验的敏感性为86%，特异性为83%。该病在巴西南部为地方病，由于没有其他诊断方法，每年通过对活检或手术标本进行解剖病理学检查来诊断一些病例。根据血清流行病学研究，两个传播疫源地的患病率分别为29.8%和66%，证明了该感染在那些流行地区广泛存在。
