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伴有下丘发育不全的中脑背侧脂肪瘤:一例报告并文献复习

Dorsal mesencephalic lipoma with inferior collicular hypoplasia: a case report and review of literature.

作者信息

Catala M, Lazareth J P, Coquille F, Binoche T

机构信息

Service d'Histologie, Embryologie et Cytogénétique/URA CNRS 2115, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.

出版信息

Clin Neurol Neurosurg. 1997 Dec;99(4):271-5. doi: 10.1016/s0303-8467(97)00091-7.

Abstract

Intracranial lipomas are rare lesions the pathogenesis of which is still a matter of debate. We report the case of a patient presenting an asymptomatic lipoma located in the quadrigeminal and supra-cerebellar cisterns. The lipoma was associated with hypoplasia of the right inferior colliculus and of the rostral part of the vermis. Analysis of the relationships between neural tube and meninges prompts us to propose that the primary event of this malformation is a defect of the neural anlage which gives rise to both nervous dysplasia and lack of meningeal induction responsible for lipoma development.

摘要

颅内脂肪瘤是罕见的病变,其发病机制仍存在争议。我们报告一例患者,其无症状性脂肪瘤位于四叠体池和小脑上池。该脂肪瘤与右侧下丘及蚓部头端发育不全相关。对神经管与脑膜之间关系的分析促使我们提出,这种畸形的主要事件是神经原基的缺陷,这导致了神经发育异常以及缺乏引发脂肪瘤形成的脑膜诱导。

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