Milbrandt E
Department of Internal Medicine, St. Vincent Hospital, Indianapolis, Indiana 46260, USA.
Clin Cardiol. 1998 Feb;21(2):123-6. doi: 10.1002/clc.4960210211.
An important element of the evaluation of patients with infective endocarditis is the determination of an infectious source. In approximately 20-45% of cases, no source is identified. Often the specific organism involved implicates the source, as is classically described by the association of S. bovis with colonic neoplasia. Other gut organisms have been reported to infect heart valves when colorectal pathology is present, but at far less frequency than S. bovis. This report deals with the case of a 75-year-old man with Enterococcus faecalis endocarditis of an unusual source--a cecal carcinoma that was causing intermittent appendiceal obstruction and infection. This case adds to previous case reports which suggest that the occurrence of enterococcal endocarditis in the absence of a classic infectious source should lead to a search for occult colorectal pathology.
感染性心内膜炎患者评估的一个重要因素是确定感染源。在大约20% - 45%的病例中,未发现感染源。通常,所涉及的特定病原体暗示了感染源,如牛链球菌与结肠肿瘤的关联所经典描述的那样。据报道,当存在结直肠病变时,其他肠道病原体也会感染心脏瓣膜,但发生频率远低于牛链球菌。本报告涉及一名75岁男性,患有粪肠球菌心内膜炎,其感染源不同寻常——是一例盲肠癌,该肿瘤导致间歇性阑尾梗阻和感染。该病例补充了之前的病例报告,提示在没有典型感染源的情况下发生肠球菌性心内膜炎时,应寻找隐匿的结直肠病变。