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精神分裂症的预后。首次入院患者的十年随访

Prognosis in schizophrenia. A ten-year follow-up of first admissions.

作者信息

Bland R C, Parker J H, Orn H

出版信息

Arch Gen Psychiatry. 1976 Aug;33(8):949-54. doi: 10.1001/archpsyc.1976.01770080067006.

DOI:10.1001/archpsyc.1976.01770080067006
PMID:949228
Abstract

Eighty-eight of 92 first admission schizophrenics from 1963, being an incidence by first admission cohort, were followed up between 1974 and 1975. Fifty-eight percent were reported as showing no social or intellectural deficit, and only 8% were unremitting institutionalized, with 51% being considered as having normal economic productivity, and 69% with a good or fair social adjustment. Despite difficulties in comparison, birth, marriage, and divorce rates appear to be not very different from those for the general population, although the percentage of married patients is lower. Deaths would seem greater than expected. Possible reasons for the improved prognosis in schizophrenia are considered to be short initial hospitalization, almost universal use of phenothiazines, use of developing community services (social and psychiatric), and generally good econimic conditions.

摘要

1963年首次入院的92名精神分裂症患者中的88名(这是首次入院队列的发病率),在1974年至1975年期间接受了随访。据报告,58%的患者没有表现出社会或智力缺陷,只有8%的患者持续被收容住院,51%的患者被认为具有正常的经济生产力,69%的患者社会适应良好或尚可。尽管比较存在困难,但出生、结婚和离婚率似乎与普通人群的这些比率没有太大差异,不过已婚患者的比例较低。死亡人数似乎比预期的要多。精神分裂症预后改善的可能原因被认为是初期住院时间短、几乎普遍使用吩噻嗪类药物、社区服务(社会和精神科)的发展以及总体良好的经济状况。

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引用本文的文献

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Age at onset and the outcomes of schizophrenia: A systematic review and meta-analysis.精神分裂症的起病年龄与结局:一项系统评价和荟萃分析。
Early Interv Psychiatry. 2017 Dec;11(6):453-460. doi: 10.1111/eip.12412. Epub 2017 Apr 27.
2
Clinical and economic outcomes of olanzapine compared with haloperidol for schizophrenia. Results from a randomised clinical trial.奥氮平与氟哌啶醇治疗精神分裂症的临床及经济学结局:一项随机临床试验的结果
Pharmacoeconomics. 1999 May;15(5):469-80. doi: 10.2165/00019053-199915050-00005.
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A multivariate analysis of mental hospital recidivism.
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J Ment Health Adm. 1995 Fall;22(4):358-67. doi: 10.1007/BF02518630.
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Clozapine: an appraisal of its pharmacoeconomic benefits in the treatment of schizophrenia.氯氮平:对其治疗精神分裂症的药物经济学效益评估
Pharmacoeconomics. 1993 Aug;4(2):131-56. doi: 10.2165/00019053-199304020-00007.
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The impact of recent rehospitalization on community adjustment.近期再次住院对社区适应的影响。
Int J Soc Psychiatry. 1981 Autumn;27(3):163-72. doi: 10.1177/002076408102700301.
6
Outcome and risks of ultra-long-term treatment with an oral neuroleptic drug. Relationship between perazine serum levels and clinical variables in schizophrenic outpatients.
Arch Psychiatr Nervenkr (1970). 1981;229(4):315-29. doi: 10.1007/BF01833160.
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[Mortality of schizophrenic patients--a study of 170 cases].[精神分裂症患者的死亡率——一项对170例病例的研究]
Soz Praventivmed. 1986;31(6):294-6. doi: 10.1007/BF02077503.
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Gender differences in age at onset of schizophrenia. An overview.精神分裂症发病年龄的性别差异。综述。
Eur Arch Psychiatry Neurol Sci. 1988 Sep;237(6):351-64. doi: 10.1007/BF00380979.
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