Sugiyama M, Ogasawara H, Kaneko H, Hishikawa T, Sekigawa I, Iida N, Hashimoto H, Hirose S
Department of Medicine, Juntendo University Izu-Nagaoka Hospital, Shizuoka, Japan.
Lupus. 1998;7(1):53-6. doi: 10.1191/096120398678919660.
Cyclosporine is widely known to be effective in cases involving both transplantation as well as a spectrum of immune-mediated diseases, although careful monitoring is required for the preemptive detection of its adverse effects. Here we report the successful treatment by extremely low dose cyclosporine (1 mg/kg per day) of two patients with thrombocytopenia in systemic lupus erythematosus.
众所周知，环孢素在移植以及一系列免疫介导疾病的治疗中均有效，不过为了预先发现其不良反应，需要进行仔细监测。在此，我们报告了两名系统性红斑狼疮血小板减少症患者通过极低剂量环孢素（每日1毫克/千克）成功治疗的病例。
