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一项针对奥地利两个群体样本中STR系统FGA的合作基因研究。

A collaborative genetic study on the STR system FGA in two Austrian population samples.

作者信息

Neuhuber F, Klintschar M, Radacher M

机构信息

Institute of Legal Medicine, University of Salzburg, Austria.

出版信息

Forensic Sci Int. 1998 Jan 9;91(1):1-6. doi: 10.1016/s0379-0738(97)00171-0.

DOI:10.1016/s0379-0738(97)00171-0
PMID:9493340
Abstract

Population genetic data of the short tandem repeat system FGA were determined by PCR analysis in two Austrian population samples, one population north of the Alps and one population south of the Alps. A total of 15 different alleles could be observed in 500 unrelated individuals. No significant differences were found between the phenotype frequencies in the two populations, as determined by R x C contingency test, so the populations could be pooled for further analysis. Both the single populations and the pooled population are in accordance with Hardy-Weinberg equilibrium. FGA proves to be very efficient for both stain analysis and paternity testing. The presented allele and genotype data allow the statistical interpretation of this system for Austrians.

摘要

通过聚合酶链反应(PCR)分析,在奥地利的两个群体样本中确定了短串联重复序列系统FGA的群体遗传数据,一个群体位于阿尔卑斯山以北,另一个群体位于阿尔卑斯山以南。在500名无关个体中总共观察到15个不同的等位基因。通过R×C列联检验确定,两个群体的表型频率之间未发现显著差异,因此可以将这两个群体合并进行进一步分析。单个群体和合并后的群体均符合哈迪-温伯格平衡。事实证明,FGA在污渍分析和亲子鉴定方面都非常有效。所呈现的等位基因和基因型数据有助于对奥地利人的该系统进行统计解释。

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