血红蛋白银泉 [β131(H9)谷氨酰胺→组氨酸]，一种在六名非裔美国人中发现的新型血红蛋白变异体。
Hb Silver Springs [beta 131(H9)Gln-->His], a new hemoglobin variant found in six African-Americans.
作者信息
Hoyer J D, Wick M J, Thibodeau S N, Kechteiger K S, Cook J D, Fairbanks V F
机构信息
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA.
出版信息
Hemoglobin. 1998 Jan;22(1):37-44. doi: 10.3109/03630269809071515.
PMID:9494046
Abstract
We report a new hemoglobin variant which we have named Hb Silver Springs. This variant results from a substitution CAG-->CAC (Gln-->His) at codon 131 of the beta chain. It was detected only by cation exchange high performance liquid chromatography. This is the fifth reported substitution at codon 131. This variant does not appear to have any clinical or hematologic manifestations.
摘要
我们报告了一种新的血红蛋白变异体，我们将其命名为Hb银泉。这种变异是由β链第131密码子处的CAG→CAC（谷氨酰胺→组氨酸）替换引起的。它仅通过阳离子交换高效液相色谱法检测到。这是第131密码子处报道的第五种替换。这种变异体似乎没有任何临床或血液学表现。
Zotero 插件