Parsonnet J
Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, California, USA.
Infect Dis Clin North Am. 1998 Mar;12(1):185-97. doi: 10.1016/s0891-5520(05)70417-7.
Helicobacter pylori infection causes peptic ulcer disease, gastric adenocarcinoma, gastric lymphoma, and probably nonulcer dyspepsia. Although the prevalence of infection is declining over time, the organism still infects approximately one half of the world's population. Only a minority will ever suffer serious consequences from their infection. This article reviews current knowledge about H. pylori and presents some of the dilemmas surrounding clinical and public health approaches to this widespread pathogen.
幽门螺杆菌感染可导致消化性溃疡病、胃腺癌、胃淋巴瘤，还可能引发非溃疡性消化不良。尽管随着时间推移感染率在下降，但该病菌仍感染着全球约一半的人口。只有少数感染者会因感染而遭受严重后果。本文回顾了关于幽门螺杆菌的现有知识，并提出了围绕这种广泛传播的病原体的临床和公共卫生应对方法的一些困境。
