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鞘脂碱基代谢。鞘氨醇-1-磷酸裂解酶:鉴定磷酸乙醇胺为产物。

Sphingolipid base metabolism. Sphinganine-1-phosphate lyase: identification of ethanolamine 1-phosphate as product.

作者信息

Shimojo T, Schroepfer G J

出版信息

Biochim Biophys Acta. 1976 Jun 22;431(3):433-46. doi: 10.1016/0005-2760(76)90210-1.

DOI:10.1016/0005-2760(76)90210-1
PMID:949485
Abstract

Ethanolamine 1-phosphate has been characterized as a product of the action of rat liver microsomal sphinganine 1-phosphate lyase on erythro-sphinganine 1-phosphate. The product was characterized by various forms of chromatography, gas-liquid chromatography-mass spectral analysis of appropriate derivatives, and by conversion to ethanolamine. The results of detailed studies of the mass spectral fragmentation of the tetra-trimethylsilyl derivative of ethanolamine 1-phosphate are also reported.

摘要

磷酸乙醇胺已被鉴定为大鼠肝脏微粒体鞘氨醇-1-磷酸裂解酶作用于赤藓糖鞘氨醇-1-磷酸的产物。该产物通过各种色谱形式、适当衍生物的气-液色谱-质谱分析以及转化为乙醇胺进行表征。还报道了对磷酸乙醇胺四-三甲基硅烷基衍生物质谱裂解的详细研究结果。

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Sphingolipid base metabolism. Sphinganine-1-phosphate lyase: identification of ethanolamine 1-phosphate as product.鞘脂碱基代谢。鞘氨醇-1-磷酸裂解酶:鉴定磷酸乙醇胺为产物。
Biochim Biophys Acta. 1976 Jun 22;431(3):433-46. doi: 10.1016/0005-2760(76)90210-1.
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Sphingolipid base metabolism. Stereospecific uptake of proton in the enzymatic conversion of sphinganine 1-phosphate to ethanolamine 1-phosphate.鞘脂碱基代谢。在鞘氨醇1-磷酸向乙醇胺1-磷酸的酶促转化过程中质子的立体特异性摄取。
J Biol Chem. 1976 Jul 25;251(14):4448-7.
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Stereospecificity of proton uptake in the enzymatic conversion of sphinganine 1-phosphate to ethanolamine 1-phosphate.鞘氨醇-1-磷酸酶促转化为乙醇胺-1-磷酸过程中质子摄取的立体特异性。
J Am Chem Soc. 1974 Feb 6;96(3):939-40. doi: 10.1021/ja00810a062.
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Microbial metabolism of amino alcohols. 1-Aminopropan-2-ol and ethanolamine metabolism via propionaldehyde and acetaldehyde in a species of Pseudomonas.氨基醇的微生物代谢。假单胞菌属中1-氨基丙-2-醇和乙醇胺通过丙醛和乙醛的代谢
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Determination of sphingosine-1-phosphate lyase activity by gas chromatography coupled to electron impact mass spectrometry.采用气相色谱-电子轰击质谱联用测定鞘氨醇-1-磷酸酶活性。
Chem Phys Lipids. 2012 Feb;165(2):225-31. doi: 10.1016/j.chemphyslip.2012.01.001. Epub 2012 Jan 12.

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