Bozzini C E, Rosenkranz A, Martinez M A, Mazzaferri E
Biomedicine. 1976 May;25(3):95-7.
The ratio "circulating red cell volume/lean body mass" was calculated in normal and hypophysectomized male rats put on paired feeding for 90 days after hypophysectomy, and in control rats both at the beginning and the end of this experimental period. Control rats at the onset of the experiment, hypophysectomized rats, and rats on the sub-maintenance level of food consumption did not show a significant difference in their red cell volumes/lean body mass ratios. These values were significantly lower than those of sham hypophysectomized rats allowed to eat ad libitum. These results suggest that the reduction in the feed intake that follows pituitary ablation may play an important role in the genesis of the post-hypophysectomy anemia.
计算了正常雄性大鼠和垂体切除术后进行90天配对喂养的去垂体雄性大鼠的“循环红细胞体积/瘦体重”比值，并在实验期开始和结束时对对照大鼠进行了计算。实验开始时的对照大鼠、去垂体大鼠以及食物摄入量处于亚维持水平的大鼠，其红细胞体积/瘦体重比值无显著差异。这些值显著低于随意进食的假手术去垂体大鼠。这些结果表明，垂体切除后随之而来的饲料摄入量减少可能在垂体切除术后贫血的发生中起重要作用。
