Coren M E, Rosenthal M, Bush A
Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London.
Arch Dis Child. 1997 Dec;77(6):522-3. doi: 10.1136/adc.77.6.522.
Five children with severe asthma requiring at least 10 mg of prednisolone daily were treated with cyclosporin. Three were weaned from prednisolone, but one quickly relapsed. One girl had her steroid dose lowered but suffered unacceptable hirsutism and one child failed to respond. Cyclosporin may be useful in refractory childhood asthma. A prospective study is required to confirm this.
5名患有严重哮喘且每日至少需要10毫克泼尼松龙治疗的儿童接受了环孢素治疗。其中3名儿童停用了泼尼松龙，但有1名很快复发。1名女孩的类固醇剂量降低了，但出现了难以接受的多毛症，还有1名儿童没有反应。环孢素可能对难治性儿童哮喘有用。需要进行一项前瞻性研究来证实这一点。
