Carella R J, Pay N, Newall J, Farina A T, Kricheff I I, Cooper J S
Cancer. 1976 Jun;37(6):2719-28. doi: 10.1002/1097-0142(197606)37:6<2719::aid-cncr2820370623>3.0.co;2-q.
The difficulty in evaluating the effectiveness of radiation therapy of primary cerebral tumors is well appreciated. Changes in the tumor size and the presence or absence of edema or necrosis during or following treatment cannot be readily evaluated by present noninterventive roentgenographic methods. At New York University Medical Center, computerized (axial) tomography (CT) has been routinely used both before and after radiation therapy with the aim of assessing, by noninterventive means, tumor response, presence or absence of edema, or necrosis. A selected series of patients is presented with correlation of the clinical findings and CT-scan results both before and after therapy. The significance of these findings and their implications in the management of cerebral tumors are discussed.
评估原发性脑肿瘤放射治疗效果存在的困难是广为人知的。目前的非介入性X线造影方法无法轻易评估治疗期间或治疗后肿瘤大小的变化以及水肿或坏死的存在与否。在纽约大学医学中心，计算机（轴向）断层扫描（CT）已常规用于放射治疗前后，目的是通过非介入性手段评估肿瘤反应、水肿或坏死的存在与否。本文展示了一系列选定患者的临床发现与治疗前后CT扫描结果的相关性，并讨论了这些发现的意义及其在脑肿瘤管理中的影响。
