Alvarez G, Araya F, Feuerhake W, Villagra R
Departamento de Ciencias Neurológicas, Facultad de Medicina, Universidad de Chile.
Rev Med Chil. 1997 May;125(5):561-6.
It has been postulated that in Chile, transient ischemic attacks (TIA) are much less frequent than in Caucasian populations. A lesser frequency of these attacks would be due to a higher frequency of intracranial atheromas, whereas an abundance of TIA would be a result of a higher prevalence of extracranial atheromas.
To study the history of TIA in a group of Chilean patients with an acute episode of cerebrovascular disease.
One hundred forty nine patients admitted to a Neurology service of a public hospital in Santiago, with an acute stroke, were studied. Patients and close relatives were interrogated about previous symptoms of TIA using a structured questionnaire.
One hundred nine patients had an ischemic and 40 patients a hemorrhagic stroke. Twenty patients with ischemic stroke had a history of TIA (18%). Fifteen out of 74 patients without a cardiac source of emboli (20%) and five out of 35 cases with an embolic source (14%) had a TIA preceding their stroke. Three out of 40 patients (8%) with hemorrhagic stroke had a history of TIA.
This study does not support nor reject the hypothesis of a Chilean pattern of cerebrovascular disease unlike that found in Northern Caucasians.
据推测,在智利,短暂性脑缺血发作(TIA)的发生率远低于白种人群体。这些发作频率较低可能是由于颅内动脉粥样硬化发生率较高,而TIA发作频繁则是颅外动脉粥样硬化患病率较高的结果。
研究一组患有急性脑血管疾病发作的智利患者的TIA病史。
对圣地亚哥一家公立医院神经科收治的149例急性中风患者进行了研究。使用结构化问卷询问患者及其近亲关于既往TIA症状的情况。
109例患者发生缺血性中风,40例患者发生出血性中风。20例缺血性中风患者有TIA病史(18%)。74例无心脏栓子来源的患者中有15例(20%),35例有栓子来源的病例中有5例(14%)在中风前有TIA发作。40例出血性中风患者中有3例(8%)有TIA病史。
本研究既不支持也不否定智利脑血管疾病模式与北欧白种人不同这一假设。