Staelens L, Van Poppel H, Vanuytsel L, Van Oosterom A, Van Damme B, Baert L
Department of Urology, University Hospitals, K.U. Leuven, Belgium.
Acta Urol Belg. 1997 Dec;65(4):39-42.
Sarcomatoid renal cell carcinoma (SRCC) is an uncommon tumor of the renal parenchyma, representing one to five percent of all primary kidney tumors. The major symptoms are the same as in the classic renal cell carcinoma: haematuria and flank pain. The tumor consists of a bimorph feature of clear cells with areas of spindle cells and giant cells, resembling a sarcoma. Immunohistochemistry and electronmicroscopy are often necessary to prove the epithelial origin of these spindle cells. Therapy is essentially surgical but in some cases there can be a benefit of chemotherapy.
肉瘤样肾细胞癌(SRCC)是一种肾实质的罕见肿瘤,占所有原发性肾肿瘤的1%至5%。主要症状与经典肾细胞癌相同:血尿和侧腹痛。肿瘤由透明细胞与梭形细胞和巨细胞区域的双形态特征组成,类似肉瘤。免疫组织化学和电子显微镜检查通常对于证实这些梭形细胞的上皮起源是必要的。治疗主要是手术,但在某些情况下化疗可能有益。