在成纤维细胞培养物中产生的异常可溶胶原蛋白。
Abnormally soluble collagen produced in fibroblasts cultures.
作者信息
Francis G, Donnelly P V, Di Ferrante N
出版信息
Experientia. 1976 Jun 15;32(6):691-3. doi: 10.1007/BF01919835.
PMID:950007
Abstract
Abnormally soluble collagen is synthesized in vitro not only by skin fibroblasts of Marfan patients but also by those of patients with Ehlers-Danlos type V and cutis laxa. The excessive solubility of collagen is corrected by the addition to the culture medium of a synthetic flavonoid, (+)- catechin.
摘要
异常可溶的胶原蛋白不仅在体外由马凡综合征患者的皮肤成纤维细胞合成，也由Ⅴ型埃勒斯-当洛综合征和皮肤松弛症患者的皮肤成纤维细胞合成。向培养基中添加一种合成类黄酮（+）-儿茶素可纠正胶原蛋白过度的溶解性。
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