Glezerman M, Lunenfeld B, Potashnik G, Oelsner G, Beer R
Fertil Steril. 1976 Jul;27(7):796-800. doi: 10.1016/s0015-0282(16)41955-2.
The ejaculatory process consists of two stages. During the first stage the semen is pumped into the posterior urethra and during the second stage the semen is propelled via the urethra through the external meatus. A pathologic second stage may lead to retrograde ejaculation of the semen into the urinary bladder. Attempts to achieve fertility in such patients can be made in two ways; namely through procedures to restore antegrade ejaculation (mainly using alpha-sympathomimetic agents) and procedures to regain viable and fertile sperm from the urinary bladder after sexual intercourse, with subsequent artificial insemination. The latter way of treatment was used in two patients who were referred for infertility and in whom retrograde ejaculation had been diagnosed. Postcoital urinary specimens were obtained by micturition and centrifuged. In one patient the sediment was washed with a nutrient solution; the other patient received alkalizing agents prior to intercourse in order to neutralize the urinary pH. The wives were inseminated on appropriate days and conceived. Both delivered healthy babies after uneventful pregnancies.
射精过程分为两个阶段。在第一阶段,精液被泵入后尿道,在第二阶段,精液通过尿道经尿道口排出。病理性的第二阶段可能导致精液逆行射入膀胱。对于此类患者,可通过两种方法尝试实现生育;即通过恢复顺行射精的程序(主要使用α-拟交感神经药)以及在性交后从膀胱中获取有活力和可育精子并随后进行人工授精的程序。后一种治疗方法应用于两名因不育前来就诊且已诊断为逆行射精的患者。性交后通过排尿获取尿液标本并进行离心。一名患者的沉淀物用营养液冲洗;另一名患者在性交前接受碱化剂以中和尿液pH值。妻子们在合适的日子接受授精并受孕。两人均在顺利妊娠后产下健康婴儿。