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正常成年男性附属腺对睾酮刺激的反应。

Response of adnexal glands to testosterone stimulation in the normal adult male.

作者信息

Dondero F, Pozza D, Mazzilli F, Isidori A

出版信息

Fertil Steril. 1976 Jul;27(7):806-11. doi: 10.1016/s0015-0282(16)41957-6.

DOI:10.1016/s0015-0282(16)41957-6
PMID:950049
Abstract

Normal male volunteers were studied in order to set up a functional exploration test based on administration of testosterone propionate for use on the adnexal glands of the male genital tract. Seminal acid phosphatase and citric acid levels showed no significant variations compared with spontaneous physiologic oscillations. Concentration and total quantity of fructose were considerably reduced. Alkaline phosphatase showed an intermediate pattern with constant values of concentration and decrease of total quantity. The hypothesis is advanced that adnexal glands possess a secretory metabolism with a maximal basal response to androgen stimulation, but with a different mechanism of action: partly adaptable at the level of the prostate and of the "all or nothing" type at the level of the vesicles.

摘要

为了建立一种基于丙酸睾酮给药的功能性探索试验,用于男性生殖道附属腺,对正常男性志愿者进行了研究。与自发的生理波动相比,精浆酸性磷酸酶和柠檬酸水平没有显著变化。果糖的浓度和总量显著降低。碱性磷酸酶呈现出一种中间模式,浓度恒定,总量下降。提出的假设是,附属腺具有一种分泌代谢,对雄激素刺激有最大的基础反应,但作用机制不同:在前列腺水平部分可适应,在精囊水平为“全或无”类型。

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