Taourel P, Perney P, Dauzat M, Gallix B, Pradel J, Blanc F, Pourcelot L, Bruel J M
Service d'Imagerie Médicale, Hôpital Saint-Eloi, Montpellier, France.
J Clin Ultrasound. 1998 Mar-Apr;26(3):131-6. doi: 10.1002/(sici)1097-0096(199803/04)26:3<131::aid-jcu4>3.0.co;2-n.
We assessed the resistance index (RI) in the superior mesenteric artery under fasting and postprandial conditions in healthy subjects and in patients with cirrhosis to determine whether the amount of change in the RI reflects the presence or severity of liver dysfunction.
Fifteen subjects with normal livers and 27 patients with cirrhosis underwent Doppler sonography of the superior mesenteric artery before and after ingesting a standard meal. The RI at baseline (fasting state) and the postprandial RI were compared between the 2 groups. The fasting RIs and post postprandial RIs changes in cirrhotic patients were correlated with the severity of disease.
No difference was found between the baseline RIs in healthy (RI = 0.85) and cirrhotic subjects (RI = 0.84), nor was there a difference in baseline RIs between subgroups of cirrhotic patients according to the severity of liver disease. The RI decreased significantly (p < 0.05) after the meal in both the healthy (13%) and cirrhotic (8%) subjects, but the postprandial decrease was significantly less pronounced (p < 0.05) in cirrhotic patients than in healthy subjects. Among cirrhotic patients, there was no correlation between the postprandial decrease of the RI and severity of liver disease.
The marked decrease in the postprandial RI in the SMA in healthy subjects is generally not seen in patients with cirrhosis, and changes in the postprandial RI do not reliably predict the severity of liver dysfunction.
我们评估了健康受试者和肝硬化患者在空腹及餐后状态下肠系膜上动脉的阻力指数（RI），以确定RI的变化量是否反映肝功能障碍的存在或严重程度。
15名肝脏正常的受试者和27名肝硬化患者在摄入标准餐后接受了肠系膜上动脉的多普勒超声检查。比较了两组在基线（空腹状态）时的RI和餐后RI。肝硬化患者的空腹RI和餐后RI变化与疾病严重程度相关。
健康受试者（RI = 0.85）和肝硬化受试者（RI = 0.84）的基线RI之间没有差异，根据肝病严重程度划分的肝硬化患者亚组之间的基线RI也没有差异。健康受试者（13%）和肝硬化患者（8%）餐后RI均显著降低（p < 0.05），但肝硬化患者餐后RI的降低明显不如健康受试者明显（p < 0.05）。在肝硬化患者中，RI餐后降低与肝病严重程度之间没有相关性。
肝硬化患者通常不会出现健康受试者餐后肠系膜上动脉RI的显著降低，餐后RI的变化不能可靠地预测肝功能障碍的严重程度。
