Ajmani R S
National Institutes of Health, National Institute on Aging, Laboratory of Cellular and Molecular Biology, Baltimore, MD 21224, USA.
Clin Hemorheol Microcirc. 1997 Nov-Dec;17(6):397-420.
Hemorheological disturbances in hypertension are the outcome of changes in red cell characteristics, their interaction in the presence of fibrinogen, and the magnitude and distribution of flow forces. Hemorheological alteration coupled with changes in biochemical variables and vessel characteristics in hypertension may affect the hemodynamic profile, which could possibly contribute to the development of hemorrhagic disorders. The complex pathophysiology of hypertension also depends upon the life style, presence of other risk factors, emotional/psychological stress, age and the genetic constitution of an individual. This review article summarizes the hemorheological changes in hypertension and their probable role in the deterioration of blood flow.
高血压中的血液流变学紊乱是红细胞特性变化、它们在纤维蛋白原存在下的相互作用以及流动力的大小和分布改变的结果。血液流变学改变与高血压中生化变量和血管特性的变化相结合，可能会影响血液动力学特征，这可能会导致出血性疾病的发生。高血压复杂的病理生理学还取决于生活方式、其他危险因素的存在、情绪/心理压力、年龄以及个体的遗传构成。这篇综述文章总结了高血压中的血液流变学变化及其在血流恶化中可能发挥的作用。
