Gachályi B, Káldor A, Kállay K
Int J Clin Pharmacol Biopharm. 1976 Apr;13(3):196-8.
The effect of 160 mg oral propranolol daily for a week on angiotensin sensitivity and plasma renin activity has been studied in ten patients with Kaplan's test and by determining renin with the radioimmunoassay. Propranolol was found to increase angiotensin activity and to reduce the plasma renin level. The results are compared with the respective effects of other antihypertensive drugs tested under identical conditions.
在10名患者中,通过卡普兰试验并采用放射免疫分析法测定肾素,研究了每日口服160毫克普萘洛尔,持续一周对血管紧张素敏感性和血浆肾素活性的影响。结果发现,普萘洛尔可增加血管紧张素活性并降低血浆肾素水平。将这些结果与在相同条件下测试的其他抗高血压药物的相应作用进行了比较。