Kindig N B, Hazlett D R
ISA Trans. 1976;15(1):79-83.
Steady state estimates of the pulmonary diffusing capacity for carbon monoxide require measurement of the uptake and the average partial pressure of CO in the lung. The expired alveolar sample obtained by different experimental methods and/or breathing patterns rarely represents the actural average alveolar partial pressure. This error in choosing the correct alveolar sample arises in the sampling time chosen by the experimental method. The time (TAV) at which the correct alveolar sample (FAV) is obtained occurs one-half of a breathing period after the effective inspiration time. If TAV and the sample time chosen by the experimental method are known then the measured diffusing capacity can be corrected to the actual diffusing capacity.
一氧化碳肺扩散容量的稳态估计需要测量一氧化碳在肺中的摄取量和平均分压。通过不同实验方法和/或呼吸模式获得的呼出肺泡样本很少能代表实际的平均肺泡分压。在选择正确的肺泡样本时出现的这种误差源于实验方法所选择的采样时间。获得正确肺泡样本（FAV）的时间（TAV）出现在有效吸气时间后的半个呼吸周期。如果已知TAV和实验方法所选择的采样时间，那么测量的扩散容量就可以校正为实际扩散容量。
