Gouado I, Mbiapo T F, Moundipa F P, Teugwa M C
Department of Biochemistry, Faculty of Science-University of Yaounde I, Cameroon.
Int J Vitam Nutr Res. 1998;68(1):21-5.
The vitamin A and E status was evaluated in 279 volunteer subjects, 3 to 75 years old (131 males and 148 females) from 8 villages in the north of Cameroon by fluorimetric methods. The results obtained showed that: the mean serum vitamin A level was 16.6 +/- 0.7 microgram % (ranging from 2.1 to 69.3 micrograms %) and vitamin E, 499.9 +/- 19.3 micrograms % (ranging from 222.7 to 1893.1 micrograms %); the percentage deficiency of vitamin A among the subjects was 71.7% and that of vitamin E was 66% (vitamin A levels < 20 micrograms/100 ml) vitamin E levels < 500 micrograms/100 ml; children of ages ranging from 3 to 15 years, constituted about 50% of the subjects and were significantly deficient in vitamin A (P < 0.001). Significant correlation was observed between the serum levels of vitamin A and E (P < 0.001). The results from this study revealed that vitamin A and E deficiencies vary from one village to another and constitute one of the major public health problems in the area.
采用荧光分析法对喀麦隆北部8个村庄的279名志愿者(年龄在3至75岁之间,其中男性131名,女性148名)的维生素A和E状况进行了评估。所得结果显示:血清维生素A平均水平为16.6±0.7微克%(范围为2.1至69.3微克%),维生素E平均水平为499.9±19.3微克%(范围为222.7至1893.1微克%);受试者中维生素A缺乏率为71.7%,维生素E缺乏率为66%(维生素A水平<20微克/100毫升,维生素E水平<500微克/100毫升);年龄在3至15岁的儿童约占受试者的50%,且维生素A严重缺乏(P<0.001)。维生素A和E的血清水平之间存在显著相关性(P<0.001)。该研究结果表明,维生素A和E缺乏情况因村庄而异,是该地区主要的公共卫生问题之一。