基于对与畸胎瘤或勃勒纳瘤相关病变的分析对卵巢黏液性肿瘤进行组织发生学考量。

A histogenetic consideration of ovarian mucinous tumors based on an analysis of lesions associated with teratomas or Brenner tumors.

作者信息

Nomura K, Aizawa S

机构信息

Department of Pathology, Jikei University, School of Medicine, Tokyo, Japan.

出版信息

Pathol Int. 1997 Dec;47(12):862-5. doi: 10.1111/j.1440-1827.1997.tb03718.x.

DOI:10.1111/j.1440-1827.1997.tb03718.x

PMID:9503468

Abstract

To investigate the histogenesis of ovarian mucinous tumors, clinicopathologic and histologic studies of mucinous tumors associated with teratomas or Brenner tumors were performed. Of 458 ovarian mucinous tumors, 13 (2.8%) and 8 (1.7%) were associated with teratomas or Brenner tumors, respectively. Of patients younger than 40 years, 5.1% had teratomas. Of patients 50 years or older, 3.5% had Brenner tumors. Histologically, nine lesions with teratomas and six lesions with Brenner tumors showed transitions or intimate admixtures of both elements. The findings of the present study suggest that teratomas and Brenner tumors make small contributions to the histogenesis of ovarian mucinous tumors but may give rise to some mucinous tumors, especially in younger patients and older patients, respectively.

摘要

为了研究卵巢黏液性肿瘤的组织发生，我们对与畸胎瘤或勃勒纳瘤相关的黏液性肿瘤进行了临床病理和组织学研究。在458例卵巢黏液性肿瘤中，分别有13例（2.8%）和8例（1.7%）与畸胎瘤或勃勒纳瘤相关。年龄小于40岁的患者中，5.1%患有畸胎瘤。年龄50岁及以上的患者中，3.5%患有勃勒纳瘤。组织学上，9例伴有畸胎瘤的病变和6例伴有勃勒纳瘤的病变显示出两种成分的过渡或紧密混合。本研究结果表明，畸胎瘤和勃勒纳瘤对卵巢黏液性肿瘤的组织发生贡献较小，但可能分别导致一些黏液性肿瘤，尤其是在年轻患者和老年患者中。