Lengani A, Coulibaly G, Laville M, Zech P
Centre hospitalier national Yalgado-Ouédraogo, Faculté des sciences de la santé, Ouagadougou, Burkina Faso.
Sante. 1997 Nov-Dec;7(6):379-83.
We identified 174 cases of chronic severe renal failure (blood creatinine > 650 mumol/l) and/or blood urea > 35 mmol/l) in a retrospective study of patients admitted to hospital between January 1989 and June 1996. Of these patients, 110 were men and 64 were women. The mean age was 36 +/- 15 years. Fifty three patients had a history of hypertension before admission, 3 patients had diabetes and 3 had gout. The most frequent clinical signs were dyspnea (55.2% of all patients), fatigue (78.2%), vomiting (63.2%) and edema (66.1%). The prevalence of hypertension was 64.9%. Glomerulonephritis was found in 42.5% of patients, chronic interstitial nephritis in 16.1%, polycystic kidney disease in 2 cases, congenital renal hypoplasia in 4 cases and unclassified kidney disease in 14.4% of cases. End-stage renal failure was complicated by heart failure in 40.2% of patients, pericarditis in 31.6%, hemorrhage of the gastrointestinal tract in 15% and infections in 22.4%. 47.7% of the patients died following admission.
在一项对1989年1月至1996年6月期间入院患者的回顾性研究中，我们识别出174例慢性严重肾衰竭患者（血肌酐>650μmol/l）和/或血尿素>35mmol/l）。这些患者中，男性110例，女性64例。平均年龄为36±15岁。53例患者入院前有高血压病史，3例有糖尿病，3例有痛风。最常见的临床症状为呼吸困难（占所有患者的55.2%）、疲劳（78.2%）、呕吐（63.2%）和水肿（66.1%）。高血压患病率为64.9%。42.5%的患者患有肾小球肾炎，16.1%患有慢性间质性肾炎，2例患有多囊肾病，4例患有先天性肾发育不全，14.4%的病例为未分类肾病。终末期肾衰竭患者中，40.2%并发心力衰竭，31.6%并发心包炎，15%并发胃肠道出血，22.4%并发感染。47.7%的患者入院后死亡。
