Trentadue N O, Kachoyeanos M K, Lea G
Children's Hospital, Medical Center of Central GA, Macon 31208, USA.
J Pediatr Nurs. 1998 Feb;13(1):15-9. doi: 10.1016/S0882-5963(98)80064-X.
Recently, patient controlled analgesia (PCA) has gained prominence in the treatment of pain for children suffering from vaso-occlusive crisis associated with sickle cell disease. Because there are several different regimens that can be used for PCA, the purpose of this study was to compare and contrast two regimens of patient controlled analgesia (PCA) in terms of safety, efficacy, and cost for the treatment of vaso-occlusive pain associated with sickle cell disease. In this study a retrospective chart review was conducted. The charts of 26 children, hospitalized on 60 different occasions in which PCA was used in the treatment of vaso-occlusive disease were included in the final sample. Patients were grouped according to the type of PCA regimen they received: high dose PCA/low basal infusion (HPCA/LBI) or low dose PCA/high basal infusion (LPCA/HBI). Children in Group 1 (HPCA/LBI) used significantly less morphine during their hospitalization, were hospitalized fewer days, and reported lower pain scores on day 2. There were considerable cost savings due to decreased length of stay, less morphine consumed overall, and fewer days required for rental of the PCA pump.
最近，患者自控镇痛（PCA）在治疗患有镰状细胞病相关血管闭塞性危机的儿童疼痛方面受到了关注。由于有几种不同的方案可用于PCA，本研究的目的是在安全性、有效性和成本方面比较和对比两种患者自控镇痛（PCA）方案，以治疗与镰状细胞病相关的血管闭塞性疼痛。在本研究中，进行了回顾性病历审查。最终样本包括26名儿童的病历，这些儿童在60个不同的场合住院，期间使用PCA治疗血管闭塞性疾病。患者根据他们接受的PCA方案类型进行分组：高剂量PCA/低基础输注（HPCA/LBI）或低剂量PCA/高基础输注（LPCA/HBI）。第1组（HPCA/LBI）的儿童在住院期间使用的吗啡明显较少，住院天数较少，并且在第2天报告的疼痛评分较低。由于住院时间缩短、总体吗啡消耗量减少以及PCA泵租赁所需天数减少，节省了大量成本。
