Thianprasit M, Chaiprasert A, Imwidthaya P
Department of Dermatology, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Curr Top Med Mycol. 1996 Dec;7(1):43-54.
Pythiosis is a cosmopolitan granulomatous disease caused by an aquatic fungus Pythium insidiosum which usually occurs in horses, cattle, dogs, cats or fishes. There have been 28 cases of human pythiosis published in the literature. Twenty three patients have been reported from all over Thailand. Human pythiosis presents in one of three clinical forms: cutaneous or subcutaneous, systemic or vascular and ophthalmic (e.g., corneal ulcer or keratitis). Systemic antibiotics or antimycotics are not effective in the treatment of this infection. A saturated solution of KI gives a beneficial result only in the subcutaneous form. Surgical removal of the source of infection is the method of therapy of vascular and ophthalmic forms.
芽生菌病是一种由水生真菌毁灭柱霉引起的世界性肉芽肿性疾病，通常发生于马、牛、狗、猫或鱼类。文献中已发表了28例人类芽生菌病病例。泰国各地已报告了23例患者。人类芽生菌病有三种临床形式之一：皮肤或皮下型、全身或血管型以及眼部型（如角膜溃疡或角膜炎）。全身使用抗生素或抗真菌药对这种感染无效。碘化钾饱和溶液仅对皮下型有有益效果。手术切除感染源是血管型和眼部型的治疗方法。
