Nakao M, Shimosawa T, Nomura S, Kuboki T, Fujita T, Murata K
Department of Psychosomatic Medicine, School of Medicine, University of Tokyo, Japan.
Am J Hypertens. 1998 Jan;11(1 Pt 1):41-5. doi: 10.1016/s0895-7061(97)00359-2.
It remains unclear whether patients with white coat hypertension are more susceptible to mental stress than are those with essential hypertension. To compare the pressor responses to mental arithmetic between the two types of hypertension, 21 untreated female outpatients, aged 42 to 64 (mean 55) years, with hypertension, were studied. After 2 weeks of self-monitoring blood pressure, 11 patients were diagnosed as having white coat hypertension and the remaining 10 patients were diagnosed as having essential hypertension. The systolic and diastolic blood pressure responses to mental arithmetic testing were significantly greater in the patients with white coat hypertension (+38 +/- 18/+24 +/- 13 mm Hg) than in those with essential hypertension (+21 +/- 8/+13 +/- 6 mm Hg). These differences also were statistically significant in controlling for the effects of age and baseline blood pressures. These data suggest that mental arithmetic testing may be a useful tool for the diagnosis of white coat hypertension.
白大衣高血压患者是否比原发性高血压患者更容易受到精神压力的影响，目前尚不清楚。为了比较这两种高血压患者对心算的升压反应，对21名年龄在42至64岁（平均55岁）的未接受治疗的高血压女性门诊患者进行了研究。在进行2周的血压自我监测后，11名患者被诊断为白大衣高血压，其余10名患者被诊断为原发性高血压。白大衣高血压患者（收缩压升高38±18/舒张压升高24±13 mmHg）对心算测试的收缩压和舒张压反应显著大于原发性高血压患者（收缩压升高21±8/舒张压升高13±6 mmHg）。在控制年龄和基线血压的影响后，这些差异也具有统计学意义。这些数据表明，心算测试可能是诊断白大衣高血压的有用工具。
