van Kaam A H, van Beek R H, Vergunst-van Keulen J G, van der Heijden J, Lutz-Dettinger N, Hop W, Sauer P J
Sophia Children's Hospital, Division of Neonatology, Rotterdam, The Netherlands.
Eur J Pediatr. 1998 Feb;157(2):132-7. doi: 10.1007/s004310050785.
Studies comparing efficacy of fibre optic phototherapy to conventional phototherapy are performed mostly in term infants and give conflicting results. This randomized prospective study compares efficacy of fibre optic phototherapy using the Ohmeda Biliblanket device to conventional fluorescent phototherapy in preterm infants. A total of 124 preterm infants with a nonhaemolytic hyperbilirubinaemia were evaluated. Stratification at randomisation was performed according to birth weight ( < 1000 g, 1000-1500 g or 1500-2000 g). Fifty-six infants received fibre optic and 68 conventional phototherapy. Efficacy was assessed by comparing the required duration of phototherapy. Median duration of phototherapy was 118 h and 114 h in the fibre optic and conventional groups respectively, the difference in which was not statistically significant. The median durations were also not significantly different within the separate weight groups. The number of infants requiring exchange transfusions was similar in both treatment groups.
The efficacy of fibre optic phototherapy in preterm infants is comparable to conventional phototherapy.
比较光纤光疗与传统光疗疗效的研究大多在足月儿中进行，结果相互矛盾。这项随机前瞻性研究比较了使用欧米达蓝光毯设备的光纤光疗与传统荧光光疗在早产儿中的疗效。共评估了124例患有非溶血性高胆红素血症的早产儿。随机分组时根据出生体重（<1000g、1000 - 1500g或1500 - 2000g）进行分层。56例婴儿接受光纤光疗，68例接受传统光疗。通过比较所需的光疗持续时间来评估疗效。光纤光疗组和传统光疗组的光疗中位持续时间分别为118小时和114小时，两者差异无统计学意义。在各个体重组内，中位持续时间也无显著差异。两个治疗组中需要换血治疗的婴儿数量相似。
光纤光疗在早产儿中的疗效与传统光疗相当。
