Kennedy D A, Hermina M S, Xanos E T, Schink J C, Hafez G R
Department of Pathology, University of Wisconsin Hospital and Clinics, Madison, USA.
Pathol Res Pract. 1997;193(10):723-6. doi: 10.1016/s0344-0338(97)80033-7.
The eleventh case of primary infiltrating ductal carcinoma of the vulva is reported with a review of the literature. The infiltrating tumor is associated with an intraductal component as well as noninvolved mammary-like glandular tissue (ectopic breast tissue) and metastases to inguinal lymph nodes. Estrogen receptor and progesterone receptor immunohistochemical staining is negative utilizing the HSCORE method. The treatment regimen is patterned after approach to node-positive breast carcinoma.
报告了第11例原发性外阴浸润性导管癌，并对文献进行了综述。浸润性肿瘤伴有导管内成分、未受累的乳腺样腺组织（异位乳腺组织）以及腹股沟淋巴结转移。采用HSCORE法进行雌激素受体和孕激素受体免疫组化染色均为阴性。治疗方案仿照治疗淋巴结阳性乳腺癌的方法制定。
