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[维生素D3和20-羟基蜕皮酮对骨骼肌中ATP、磷酸肌酸、肌肽和Ca2+含量的影响]

[Effect of vitamin D3 and 20-hydroxyecdysone on the content of ATP, creatine phosphate, carnosine and Ca2+ in skeletal muscles].

作者信息

Kholodova Iu D, Tugaĭ V A, Zimina V P

机构信息

A.V. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv.

出版信息

Ukr Biokhim Zh (1978). 1997 May-Jun;69(3):3-9.

PMID:9505354
Abstract

The effect of vitamin D3, 20-hydroxyecdysone and extract from Serratula coronata containing 20-hydroxyecdysone on the level of basic metabolites in the skeletal muscles of rats has been studied. It was shown that development of D-hypovitaminosis is accompanied by the decrease in content of ATP, creatine phosphate, carnosine, and by the increase of Ca2+ content. Against the background of D-hypovitaminosis the 20-hydroxyecdysone and the extract from Serratula coronata which contains 20-hydroxyecdysone promote the increase of the amount of these metabolites up to the control of one and normalize Ca2+ content in them.

摘要

研究了维生素D3、20-羟基蜕皮酮以及含有20-羟基蜕皮酮的麻花头提取物对大鼠骨骼肌中基本代谢产物水平的影响。结果表明,维生素D缺乏症的发展伴随着三磷酸腺苷(ATP)、磷酸肌酸、肌肽含量的降低以及钙离子(Ca2+)含量的增加。在维生素D缺乏症的背景下,20-羟基蜕皮酮以及含有20-羟基蜕皮酮的麻花头提取物可促使这些代谢产物的量增加至对照水平,并使其中的钙离子含量恢复正常。

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