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中老年期轻度痴呆综合征

[Mild dementia syndrome in middle and old age].

作者信息

Zharikov G A

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1998;98(1):22-6.

PMID:9505399
Abstract

95 elderly and senile patients with mild dementia were followed up: 20 patients with Alzheimer's disease, 25 patients with senile dementia of Alzheimer's type (DAT), 25 patients with vascular dementia (VD), 25 patients with combined vascular and Alzheimer's type of dementia (DAT/VD). Follow-up of patients for 1 and 3 years demonstrated that the diagnosis of mild dementia according to CDR and ICD-10 criteria had a differential-diagnostic specificity and reliability. It was also noticed that the nosologic qualification of mild dimentia syndrome was difficult or even impossible in patients with DAT/VD in conditions of a single examination. Only follow-up studies (during 3 years as a rule) may give a chance to define the diagnostic belonging of mild dementia syndrome more precisely.

摘要

对95例患有轻度痴呆的老年患者进行了随访:20例阿尔茨海默病患者,25例阿尔茨海默型老年性痴呆(DAT)患者,25例血管性痴呆(VD)患者,25例血管性与阿尔茨海默型混合性痴呆(DAT/VD)患者。对患者进行1年和3年的随访表明,根据CDR和ICD-10标准诊断轻度痴呆具有鉴别诊断的特异性和可靠性。还注意到,在单次检查的情况下,DAT/VD患者的轻度痴呆综合征的疾病分类鉴定困难甚至不可能。只有随访研究(通常为3年)才可能有机会更准确地确定轻度痴呆综合征的诊断归属。

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