Chauhan A, Vu E, Ricci D R, Buller C E, Moscovich M D, Monkman S, Penn I M
Vancouver Hospital and Health Sciences Centre, University of British Columbia, Canada.
Heart. 1998 Jan;79(1):29-33. doi: 10.1136/hrt.79.1.29.
To examine the immediate and intermediate term clinical outcome of multiple coronary stenting.
Consecutive patients were prospectively entered on a dedicated database. Follow up information was obtained from outpatient and telephone interviews with patients and family physicians.
A tertiary referral centre.
140 consecutive patients underwent multiple coronary stenting between April 1994 and November 1996. Most patients had unstable coronary syndromes.
Death, cerebrovascular accidents, myocardial infarction (MI), coronary artery bypass surgery (CABG), and repeat angioplasty (PTCA).
The angiographic success rate was 100% and the clinical procedural success rate 93%. The mean (SD) follow up was 11.9 (7.2) months (range 2-32). The mean (SD) number of stents per patient was 2.4 (0.7). The mean (SD) number of lesions treated per patient was 1.4 (0.6). There were four in-hospital deaths (2.9%) and five patients (3.6%) had an MI before hospital discharge. All in-hospital deaths occurred in patients presenting with an acute MI and cardiogenic shock. Three patients (2.2%) had a late MI. One patient with stent thrombosis underwent emergency CABG. Three patients (2.2%) underwent late CABG. Eight patients (5.7%) had a repeat PTCA. Eighty three patients (61.5%) were asymptomatic at follow up and 121 (86.4%) were free from major clinical events.
In an era of increased operator experience, high pressure stent deployment, and reduced anticoagulation with antiplatelet treatment alone, multiple coronary stenting may be performed with a high procedural success rate and good intermediate term outcome.
研究多次冠状动脉支架置入术的近期和中期临床结果。
连续纳入患者并前瞻性地录入专用数据库。通过对患者及其家庭医生进行门诊和电话访谈获取随访信息。
一家三级转诊中心。
1994年4月至1996年11月期间,140例连续患者接受了多次冠状动脉支架置入术。大多数患者患有不稳定型冠状动脉综合征。
死亡、脑血管意外、心肌梗死(MI)、冠状动脉旁路移植术(CABG)以及重复血管成形术(PTCA)。
血管造影成功率为100%,临床手术成功率为93%。平均(标准差)随访时间为11.9(7.2)个月(范围2 - 32个月)。每位患者置入支架的平均(标准差)数量为2.4(0.7)个。每位患者治疗病变的平均(标准差)数量为1.4(0.6)个。有4例住院死亡(2.9%),5例患者(3.6%)在出院前发生心肌梗死。所有住院死亡均发生在急性心肌梗死并伴有心源性休克的患者中。3例患者(2.2%)发生晚期心肌梗死。1例发生支架血栓形成的患者接受了急诊冠状动脉旁路移植术。3例患者(2.2%)接受了晚期冠状动脉旁路移植术。8例患者(5.7%)接受了重复血管成形术。83例患者(61.5%)在随访时无症状,121例患者(86.4%)无重大临床事件。
在术者经验增加、采用高压支架置入以及仅用抗血小板治疗减少抗凝的时代,多次冠状动脉支架置入术可获得较高的手术成功率和良好的中期结果。