Waters D J, Honeckman A, Cooley D M, DeNicola D
Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907, USA.
J Am Anim Hosp Assoc. 1998 Mar-Apr;34(2):103-8. doi: 10.5326/15473317-34-2-103.
Despite the highly malignant nature of feline mammary carcinoma, few cases of skeletal metastasis have been reported. In this paper, a case of feline mammary carcinoma with skeletal metastasis to a distal limb is presented. The pertinent literature on feline mammary carcinoma and bone metastases is reviewed. Although the metastases of carcinomas in dogs and humans usually exhibit a proximal skeletal distribution, cats are more likely to develop distal extremity lesions. Clinicians need to have an index of suspicion that skeletal metastases may be responsible for lameness in elderly cats. Further investigation of the comparative aspects of bone metastases in cats and other species may elucidate the factors that regulate the development of skeletal metastases.
尽管猫乳腺癌具有高度恶性，但骨骼转移的病例报道较少。本文报告了一例猫乳腺癌发生远端肢体骨骼转移的病例。并对猫乳腺癌和骨转移的相关文献进行了综述。虽然犬类和人类的癌转移通常表现为近端骨骼分布，但猫更易发生远端肢体病变。临床医生需要怀疑骨骼转移可能是老年猫跛行的原因。进一步研究猫与其他物种骨转移的比较方面，可能会阐明调节骨骼转移发生发展的因素。
