Contreras A, Corrales J C, Sánchez A, Adúriz J J, González L, Marco J
Departamento de Patología Animal, Facultad de Veterinaria, Universidad de Murcia, Spain.
Vet Rec. 1998 Feb 7;142(6):140-2. doi: 10.1136/vr.142.6.140.
The presence of caprine arthritis and encephalitis (CAE) in Spain has never been officially acknowledged but it is suspected. Goats have been imported from other European countries with a high prevalence of the disease, mainly France, and they might have introduced the disease into the indigenous goat population. A serological survey of caprine arthritis and encephalitis virus antibodies was carried out in 22 volunteer dairy Murciano-Granadina goat herds; 2513 lactating goats were tested with an agar gel immunodiffusion test, and 12.1 per cent were found to be positive. Five of the herds were free of infection, six had a low prevalence of the disease, five had a medium prevalence and six had a high prevalence. Five seropositive goats with clinical signs of CAE were studied. Macroscopic and microscopic lesions similar to those described for CAE were detected in all five goats and a cytopathic effect typical of CAE virus was observed in primary explant cultures from four of them.
西班牙从未正式承认存在山羊关节炎脑炎（CAE），但对此存在怀疑。该国从该病高发的其他欧洲国家（主要是法国）进口了山羊，这些山羊可能将该病传入了本地山羊群体。对22个自愿参与的穆尔西亚诺-格拉纳迪纳奶山羊群进行了山羊关节炎脑炎病毒抗体的血清学调查；用琼脂凝胶免疫扩散试验对2513只泌乳山羊进行了检测，发现12.1%呈阳性。其中5个畜群未感染，6个畜群该病患病率低，5个畜群患病率中等，6个畜群患病率高。对5只出现CAE临床症状的血清阳性山羊进行了研究。在所有5只山羊中均检测到与CAE描述相似的宏观和微观病变，并且在其中4只山羊的原代外植体培养物中观察到了CAE病毒典型的细胞病变效应。
