Eholie S P, N'gbocho L, Bissagnene E, Coulibaly M, Ehui E, Kra O, Assoumou A, Aoussi E, Kadio A
Service de maladies infectieuses et tropicales, CHU de Treichville, Abidjan, Côte d'Ivoire.
Bull Soc Pathol Exot. 1997;90(5):307-11.
During 1995, among 1105 HIV patients explored in our department, 64 presented a deep fungic infection (5.8%). The yeast was searched for in cerebrospinal fluid, blood, urine, and bronchoalveolar aspiration. Isolated germs were Cryptococcus neoformans (95%), Candida tropicalis (1 case), Saccharomyces cerevisiae (1 case) et Aspergillus fumigatus (1 case). Results of treatment with amphotericin B were: recovery (9%), clinical success (11%), out of sight (14%), letality (66%), relapse (23%) and side effects (19%). We emphasized diagnostical and therapeutical difficulties, and bad prognostic of mycoses in patients with AIDS.
1995年期间,在我科诊治的1105例艾滋病毒患者中,64例出现深部真菌感染(5.8%)。在脑脊液、血液、尿液和支气管肺泡灌洗液中查找酵母菌。分离出的病菌有新型隐球菌(95%)、热带假丝酵母菌(1例)、酿酒酵母(1例)和烟曲霉(1例)。两性霉素B治疗结果为:痊愈(9%)、临床成功(11%)、病情隐匿(14%)、死亡(66%)、复发(23%)和出现副作用(19%)。我们强调了艾滋病患者真菌病诊断和治疗的困难以及预后不良。