Shore S E, Moore J K
Kresge Hearing Research Institute, Department of Otolaryngology, The University of Michigan, Ann Arbor 48109-0506, USA.
Hear Res. 1998 Feb;116(1-2):33-42. doi: 10.1016/s0378-5955(97)00207-4.
Anterograde and retrograde transport of fluorogold was used to trace input to the superficial granule cell layer of the ventral cochlear nucleus in the guinea pig. Infusion of fluorogold into the labyrinth resulted in heavy labeling of eighth nerve axons and their terminals in the ventral cochlear nucleus, but only a few labeled axons entered the granule cell layer. Injections of fluorogold restricted to the granule cell layer retrogradely labeled neurons in the ipsilateral lateral superior olivary nucleus, in the periolivary region predominantly contralaterally, and in the inferior colliculus predominantly ipsilaterally. Labeled neurons were also present in the ipsilateral ventral cochlear nucleus, but this may be due to interruption of axons of passage in the lateral ventrotubercular tract. Overall this study demonstrates very restricted direct cochlear input to the granule cell region, but provides evidence for projections from several brainstem auditory nuclei.
运用荧光金的顺行和逆行运输来追踪豚鼠腹侧耳蜗核浅层颗粒细胞层的传入。将荧光金注入迷路导致第八神经轴突及其在腹侧耳蜗核的终末大量标记，但只有少数标记轴突进入颗粒细胞层。局限于颗粒细胞层注射荧光金可逆行标记同侧外侧上橄榄核、主要是对侧的橄榄周区域以及主要是同侧的下丘中的神经元。标记神经元也存在于同侧腹侧耳蜗核中，但这可能是由于外侧腹结节束中通过的轴突中断所致。总体而言，这项研究表明耳蜗对颗粒细胞区域的直接输入非常有限，但为来自几个脑干听觉核团的投射提供了证据。
