Epstein N E
North Shore University Hospital, Manhasset, New York, USA.
Surg Neurol. 1998 Mar;49(3):246-52. doi: 10.1016/s0090-3019(97)00285-1.
Between 1989 to 1993, clinical instability associated with pseudarthrosis was evaluated in 76 patients with cervical ossification of the posterior longitudinal ligament (OPLL). Average 2.5 level extended anterior diskectomy and fusion and average 3.0 level anterior corpectomy and fusion were performed without anterior plate instrumentation using iliac crest or fibular strut autografts.
Fusion versus pseudarthrosis resulting in clinical instability, as defined by White and Panjabi, was assessed using flexion and extension X-rays 3 and 6 months post-operatively. Radiographic instability was defined by > 3.5 mm. of sagittal plane translation (or 20%) and > 20 degrees of sagittal plane rotation on dynamic X-rays. Two and 3 dimensional (D) computed tomography (CT) scans, also obtained 3 months postoperatively, either confirmed fusion or indicated failed bony union. The average clinical follow up period was 3 years (range, 25-52 months).
Three months postoperatively, dynamic X-rays in 20 patients demonstrated radiographic instability consistent with pseudarthrosis, whereas 2 and 3D CT studies indicated a lack of fusion. At 6 months, flexion and extension X-rays revealed that 10 patients were fused and that another 7 were clinically stable despite persistent, irregular, linear lucencies at graft/body interfaces. Three (4%) patients with clinical instability associated with pseudarthrosis required secondary posterior wiring and fusion.
Only 4% of patients undergoing average 2.75 level anterior OPLL surgery without anterior plate instrumentation required secondary posterior wiring and fusion for clinical instability associated with pseudarthrosis.
1989年至1993年期间,对76例颈椎后纵韧带骨化症(OPLL)患者与假关节相关的临床不稳定情况进行了评估。平均2.5个节段进行了前路椎间盘切除融合术,平均3.0个节段进行了前路椎体次全切除融合术,均未使用前路钢板内固定,采用了髂嵴或腓骨支撑自体骨移植。
根据White和Panjabi的定义,在术后3个月和6个月通过屈伸位X线片评估融合与导致临床不稳定的假关节情况。影像学不稳定定义为动态X线片矢状面平移>3.5 mm(或20%)以及矢状面旋转>20度。术后3个月还进行了二维和三维(D)计算机断层扫描(CT),以确认融合情况或提示骨愈合失败。平均临床随访期为3年(范围25 - 52个月)。
术后3个月,20例患者的动态X线片显示与假关节一致的影像学不稳定,而二维和三维CT研究表明缺乏融合。6个月时,屈伸位X线片显示10例患者融合,另外7例尽管移植骨/椎体界面持续存在不规则线性透亮区,但临床稳定。3例(4%)与假关节相关的临床不稳定患者需要二期后路钢丝固定和融合。
在未使用前路钢板内固定的情况下,平均进行2.75个节段前路OPLL手术的患者中,仅4%因与假关节相关的临床不稳定需要二期后路钢丝固定和融合。