Terasako K, Sasai S
Division of Anaesthesia, Shiga Adult Disease Center, Kyoto, Japan.
Acta Anaesthesiol Scand. 1998 Feb;42(2):270-1. doi: 10.1111/j.1399-6576.1998.tb05122.x.
Surgery in the presence of uncontrolled polycythemia vera is associated with a high incidence of perioperative hemorrhage and postoperative venous thromboses. Control prior to surgery reduces the frequency of perioperative complications. A 73-year-old women suffering from polycythemia vera was scheduled for subtotal gastrectomy. Her platelet count before surgery was slightly elevated but bleeding time was prolonged. To manage the current case of polycythemia vera, hydroxyurea was effective for the control of hematocrit and transfusion of platelet concentrates was effective for hemostasis.
在真性红细胞增多症未得到控制的情况下进行手术,围手术期出血和术后静脉血栓形成的发生率很高。术前进行控制可降低围手术期并发症的发生率。一名73岁患有真性红细胞增多症的女性计划进行胃次全切除术。她术前的血小板计数略有升高,但出血时间延长。对于当前这例真性红细胞增多症患者,羟基脲对控制血细胞比容有效,输注浓缩血小板对止血有效。