Hansson M, Gänsler T, Salomonsson G
Department of Applied Electronics, Lund University, Sweden.
IEEE Trans Biomed Eng. 1998 Mar;45(3):323-34. doi: 10.1109/10.661157.
This paper describes a method to measure changes in the mid-latency auditory evoked potential (MLAEP) during anesthesia. It is claimed that the position of the Nb-trough of the MLAEP indicates the level of consciousness. The component shows graded changes corresponding to the dose of anesthetic and it exhibits stable reproducible properties between different subjects. We propose a system that reduces the disturbances in an averaged MLAEP using fewer realizations than in the standard averaging procedure. The resulting smoothing error is reduced if the number of stimulus is decreased. Unfortunately, the variance of the waveform estimate is, thereby, increased. An improved method must be used in order to estimate the Nb-trough within a prescribed time interval of one minute. The procedure is based on inherent properties of the MLAEP and the noise. A simulation and examples of the performance on real data recorded during surgery are shown.
本文描述了一种测量麻醉期间中潜伏期听觉诱发电位（MLAEP）变化的方法。据称，MLAEP的Nb波谷位置表明意识水平。该成分呈现出与麻醉剂量相对应的分级变化，并且在不同受试者之间具有稳定的可重复性。我们提出了一种系统，该系统使用比标准平均程序更少的实现次数来减少平均MLAEP中的干扰。如果刺激次数减少，由此产生的平滑误差会降低。不幸的是，波形估计的方差会因此增加。为了在规定的一分钟时间间隔内估计Nb波谷，必须使用一种改进的方法。该程序基于MLAEP和噪声的固有特性。展示了对手术期间记录的真实数据的模拟和性能示例。
