Iarustovskiĭ M B, Grigor'iants R G, Timokhov V S, Abramian M V, Mikhaĭlova I L, Volkova S S, Banketov Ia V, Golenishchev I I, Iakovleva I I
Anesteziol Reanimatol. 1997 Nov-Dec(6):40-6.
The efficacy of continuous methods of renal substitute therapy (RST) in patients with multiple organ failure is assessed. The patients were divided in 2 groups administered different types of PST. Group 1 were 16 patients subjected to RST by peritoneal dialysis, in group 2 (n = 16) GP and/or GDP were used. Hemodynamics, hematological and biochemical values, and clearance of inflammation mediators were monitored and hemohydrobalance and complications of therapy assessed in the course of RST. Both RST methods proved to be highly effective. The possibility of differentiated use of peritoneal dialysis and GP/GDP permits an individual approach to treatment, and equally high efficacy of both methods solves the problem of treating total renal insufficiency in the majority of patients with multiple organ failure following cardiovascular surgery.
评估了连续性肾脏替代疗法(RST)在多器官功能衰竭患者中的疗效。将患者分为两组,给予不同类型的持续性肾脏替代治疗(PST)。第1组为16例接受腹膜透析进行RST的患者,第2组(n = 16)使用血液滤过(GP)和/或血液滤过透析(GDP)。在RST过程中监测血流动力学、血液学和生化指标,以及炎症介质清除情况,并评估血液水盐平衡和治疗并发症。两种RST方法均证明非常有效。腹膜透析和血液滤过/血液滤过透析差异化使用的可能性允许采用个体化治疗方法,且两种方法同样高的疗效解决了大多数心血管手术后多器官功能衰竭患者的完全性肾功能不全治疗问题。